John and Abigail Adams

Thomas and Martha Jefferson (she was not a First Lady as she had died many years earlier)

John Quincy and Lousia Adams

Andrew and Rachel Jackson (she was not a First Lady as she died just prior to the inauguration)

James and Sarah Polk

Abraham and Mary Lincoln

Rutherford and Lucy Hayes

Chester and Ellen Arthur(she was not a First Lady as she died shortly before he assumed office.)

Benjamin and Caroline Harrison

Grover and Frances Cleveland

William and Ida McKinley

Theodore and Alice Roosevelt(Alice was not a First Lady as she died after only four years of marriage. Theodore then married his long time friend Edith Carrow.)

Calvin and Grace Coolidge

Woodrow and Ellen Wilson (When Ellen died in 1914 and while in office Woodrow married Edith Galt after a 9 month courtship.)

Franklin and Eleanor Roosevelt

Richard and Pat Nixon

Ronald and Nancy Reagan

George and Barbara Bush